Publications

• Zdouc, MM; Blin, K; +288 authors including Avalon, NE. “MIBiG 4.0: Advancing Biosynthetic Gene Cluster Curation through Global Collaboration.” Nucleic Acids Research, 53(D1), d678-d690. 6 January 2025. DOI:10.1093/nar/gkae1115; PMCID: PMC11701617 

• Alexander, KL; Naman, CB; Iwasaki, A; Leao, T; Reher, R; Petras, D; Kim, H; Ternon, E; Caro-Diaz, E; Glukhov, E; Mitrevska, JA; Avalon, NE; Duggan, B; Gerwick, L; Gerwick, WH; “Fatuamide A, a Hybrid PKS/NRPS Metallophore from an American Samoan Cyanobacterium Leptolyngbya sp.” Journal of Natural Products. 29 January 2025. DOI: 10.1021/acs.jnatprod.4c01051; PMID: 39879528.

• El Abiead, Y; Strobel, M; Payne, T; Fahy, E; O’Donovan, C; Subramamiam, S; Vizcaino, JA; Zuffa, S; Xing, S; Mannochio-Russo, H; Mohanty, I; Zhao, HN; Caraballo-Rodriguez, AM; Gomes, PWP; Avalon, NE; Dorrestein, PC; Wang, M. “Enabling pan-repository reanalysis for big data science of public metabolomics data.” (In Review. Also available on ChemRxiv with DOI: 10.26434/chemrxiv-2024-jt46s).

• Ryu, B; Glukhov, E; Teixeira, TR; Caffrey, CR; Madiyan, S; Joseph, V; Avalon, NE; Leber, CA; Naman CB; Gerwick, WH. “The Kavaratamides: Discovery of Linear Lipodepsipeptides from the Marine Cyanobacterium Moorena bouillonii using a Comparative Chemogeographic Analysis.” DOI: 10.1021/acs.jnatprod.4c00242; PMCID: PMC11217931.

• Avalon, NE;* Reis, MA;* Thornburg, CC;* Williamson, RT;  Petras, D; Aron, AT; Al-Hindy, M; Mitrevska, J; Ferreira, L; Morais, J; El Abiead, Y; Glukhov, E; Alexander, KL; Vulpanovici, FA; Bertin, MJ; Whitner, S; Choi, H; Spengler, G; Blinov, K; Kew, WR; Pasa-Tolic, L; Dorrestein, PC; Vasconcelos, V; Gerwick, L; McPhail, KL; Gerwick; WH. “Leptochelins A-C, cytotoxic metallophores produced by geographically dispersed Leptothoe sp. marine cyanobacteria.” Journal of the American Chemical Society. 25 June 2024. DOI: 10.1021/jacs.4c05399; PMCID: PMC11240249 (*co-first authors; equally contributed to the work.)

• Ngo, T-E; Ecker, A; Guild, A; Remmel, A; Boudreau, P; Alexander, KL; Naman, B; Glukhov, E; Avalon, NE; Shende, VV; Gerwick, L; Gerwick WH. “Structure and Biosynthesis of Hectoramide B, an Upregulated Linear Depsipeptide from the Marine Cyanbacterium Moorena producens JHB,” ACS Chemical Biology. 8 February 2024. DOI: doi.org/10.1021/acschembio.3c00391. PMID: 38330248.

• Zuffa, S; Schmid, R; Bauermeister, A; Gomes, PWP; Caraballo-Rodriguez, AM; El Abiead, Y; Aron, AT; Gentry, EC; Zemlin, J; Meehan, MJ; Avalon, NE; +92 authors. “MicrobeMASST: A Taxonomically-informed Mass Spectrometry Search Tool for Microbial Metabolomics Data,” Nature Microbiology. 5 February 2024. DOI: 10.1038/s41564-023-01575-9. PMCID: 38316926.

• Bittremieux, W; Avalon, NE; Thomas, SP; Kakhkhorov, SA; Aksenov, AA; Gomes, PWP; Aceves, CM Andrés; Caraballo Rodríguez, M; Gauglitz, JM; Gerwick, WH; Jarmusch, AK; Kaddurah-Daouk, RF; Kang, KB; Kim, HW; Kondić, T; Mannochio-Russo, H; Meehan, MJ; Melnik, AV; Nothias, L; O’Donovan, C; Panitchpakdi, M; Petras, D; Schmid, R; Schymanski, EL; van der Hooft, JJJ; Weldon, KC; Yang, H; Zemlin, J; Wang, M; Dorrestein, PC. “Open Access Repository-Scale Propagated Nearest Neighbor Suspect Spectral Library for Untargeted Metabolomics,” Nature Communications. 20 December 2023. DOI: 10.1038/s41467-023-44035-y.

• Lukowski, A; Hubert, F; Ngo, TE; Avalon, NE; Gerwick, WH; Moore, BS. “Enzymatic Halogenation of Terminal Alkynes.” Journal of the American Chemical Society. 18 August 2023, 145, 34, 18716–18721. DOI: 10.1021/jacs.3c05750, PMCID: PMC10486310.

• Avalon, NE; Gerwick, WH. “Plant Sources of Drugs and Chemicals.” Reference Module in Life Sciences, Elsevier, 2023. ISBN 9780128096338, DOI: 10.1016/B978-0-12-822562-2.00107-9.

• Terlouw BR, Blin K, Navarro-Muñoz JC, Avalon NE, Chevrette MG, Egbert S, Lee S, Meijer D, Recchia MJJ, Reitz ZL, van Santen JA, Selem-Mojica N, Tørring T, Zaroubi L, Alanjary M, Aleti G, Aguilar C, Al-Salihi SAA, Augustijn HE, Avelar-Rivas JA, Avitia-Domínguez LA, Barona-Gómez F, Bernaldo-Agüero J, Bielinski VA, Biermann F, Booth TJ, Carrion Bravo VJ, Castelo-Branco R, Chagas FO, Cruz-Morales P, Du C, Duncan KR, Gavriilidou A, Gayrard D, Gutiérrez-García K, Haslinger K, Helfrich EJN, van der Hooft JJJ, Jati AP, Kalkreuter E, Kalyvas N, Kang KB, Kautsar S, Kim W, Kunjapur AM, Li YX, Lin GM, Loureiro C, Louwen JJR, Louwen NLL, Lund G, Parra J, Philmus B, Pourmohsenin B, Pronk LJU, Rego A, Rex DAB, Robinson S, Rosas-Becerra LR, Roxborough ET, Schorn MA, Scobie DJ, Singh KS, Sokolova N, Tang X, Udwary D, Vigneshwari A, Vind K, Vromans SPJM, Waschulin V, Williams SE, Winter JM, Witte TE, Xie H, Yang D, Yu J, Zdouc M, Zhong Z, Collemare J, Linington RG, Weber T, Medema MH. “MIBiG 3.0: a community-driven effort to annotate experimentally validated biosynthetic gene clusters.” Nucleic Acids Research. 6 January 2023 18:gkac1049. DOI: 10.1093/nar/gkac1049. PMCID: PMC9825592.

• Welsch, JT.; Smalley, TB; Matlack, JK; Avalon, NE; Binning, JM; Johnson, MP; Allcock, AL; Baker, BJ. Tuaimenals B-H, Cytotoxic Meroterpenes from the Irish Deep-Sea Soft Coral Duva florida with Bioactivity Against Cervical Cancer. Journal of Natural Products. 29 December 2022, 86, 1, 182-190. DOI: 10.1021/acs.jnatprod.2c00898. PMCID: PMC9887596.

• Avalon, NE; Murray AE; Baker, BJ. “Integrated metabolomic-genomic workflows accelerate microbial natural product discovery.” Analytical Chemistry, 6 September 2022. DOI: 10.1021/acs.analchem.2c02245; PMCID: PMC9453739

• Avalon, NE; Nafie, J; De Marco Verissimo, C; Warrensford, LC; Dietrick, SG; Pittman, AR; Young, RM; Kearns, FL; Smalley, T; Binning, JM; Dalton, JP; Johnson, MP; Woodcock, HL; Allcock, AL; Baker, BJ. “Tuaimenal A, a meroterpene from the Irish Deep-Sea Soft Coral Duva florida, displays inhibition of the SARS-CoV-2 3CLpro enzyme.” Journal of Natural Products, 27 May 2022. DOI: 10.1021/acs.jnatprod.2c00054; PMCID: PMC9127705 

• Avalon, NE; Murray, AE Daligault, HE; Lo, C; Davenport, KW; Dichosa, AEK; Chain, PSG; Baker, BJ. “Bioinformatic and mechanistic analysis of the palmerolide PKS-NRPS biosynthetic pathway from the microbiome of an Antarctic ascidian.” Frontiers in Chemistry, 24 December 2021. DOI: 10.3389/fchem.2021.802574; PMCID: PMC8739492

• Murray, AE; Lo, C; Daligault, HE; Avalon, NE; Read, R; Davenport, KW; Higham, ML; Kunde, Y; Dichosa, AEK; Baker, BJ; Chain, PSG. “Discovery of an Antarctic ascidian-associated uncultivated Verrucomicrobia with antimelanoma palmerolide biosynthetic potential.” mSphere, 1 December 2021. DOI: 10.1128/mSphere.00759-21; PMCID: PMC8636102

• Kokkaliari, S;* Avalon, NE;* Herrera, K; Young, R; Yang, B; Welsh, J; Deitrich, S; Baker, B.J. “Marine Natural Products with Bioactivity Against Neglected Tropical Diseases.” Marine Natural Products. H. Kiyota (ed.), Springer Berlin Heidelberg: Berlin, Heidelberg, 12 May 2021. ISBN978-981-16-4636-2; DOI: https://doi.org/10.1007/7081_2021_56. (*co-first authors; equally contributed to the work.)

• Murray, AE; Avalon, NE; Bishop, L; Davenport, K; Delage, E; Dichosa, AEK; Eveillard, D; Higham, M; Kokkaliari, S; Lo, C; Risenfield, C; Young, R; Chain, PSG; Baker, BJ. “Uncovering the core microbiome and distributions of palmerolide in Synoicum adareanum across the Anvers Island archipelago, Antarctica.” Marine Drugs, 2 June 2020, 18 (6), 298. DOI: 10.3390/md18060298; PMCID: PMC7345734

Burrell C, Avalon, NE, Siegel J, Pizzi M, Dutta T, Charlesworth MC, Freeman WD. “Precision medicine of aneurysmal subarachnoid hemorrhage, vasospasm and delayed cerebral ischemia.” Expert Reviews in Neurotherapeutics. 11 November 2016; 16(11): 1251-1262. DOI: 10.1080/14737175.2016.1203257; PMCID: PMC5573230

• Carrigan W.V. 3rd, Barrett K, Freeman W.D., Avalon, NE. “Multimodal CT to differentiate acute ischemic stroke from stroke mimics.” Neurohospitalist. 2 April 2012(2):60-1. DOI: 10.1177/1941874412439582; PubMed PMID: 23983864.